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• 11:48, 13 March 2026 Ostermayer talk contribs created page Alkali ingestion (Created page with "==Background== *Alkali (caustic/corrosive) ingestion refers to oral exposure to substances with a pH ≥ 12, which cause '''liquefactive necrosis''' — saponification of fats, protein denaturation, and cell membrane destruction that penetrates deeply into tissue<ref name="hoffman">Hoffman RS, Burns MM, Gosselin S. Ingestion of caustic substances. ''N Engl J Med''. 2020;382(18):1739-1748. PMID 32348644.</ref> *Unlike acids (which cause coagulative necrosis with a protect...")