Liver failure

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• Acute hepatic failure

📊 MELD Score Calculator [show]

MELD Score

MELD Score (Model for End-Stage Liver Disease)

Parameter	Value
Creatinine (mg/dL) — capped at 4.0
Bilirubin (mg/dL)
INR
On Dialysis (2× in past week or CVVHD)	1 No   Yes (Cr set to 4.0)
MELD Score

Interpretation — 3-Month Mortality
<10	~2% mortality.
10–19	~6% mortality.
20–29	~20% mortality.
30–39	~53% mortality.
≥40	~71% mortality. Consider transplant evaluation.

References

Kamath PS, Wiesner RH, Malinchoc M, et al. A model to predict survival in patients with end-stage liver disease. Hepatology. 2001;33(2):464-470. PMID 11172350. Wiesner R, Edwards E, Freeman R, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology. 2003;124(1):91-96. PMID 12512033. Formula: MELD = 10 × [0.957 × ln(Cr) + 0.378 × ln(Bilirubin) + 1.120 × ln(INR) + 0.643]. Minimum lab values set to 1.0. Cr capped at 4.0.

📊 Child-Pugh Score Calculator [show]

Child-Pugh Score

Child-Pugh Score

Factor	1 Point	2 Points	3 Points
Bilirubin (mg/dL)	1 <2	2–3	>3
Albumin (g/dL)	1 >3.5	2.8–3.5	<2.8
INR	1 <1.7	1.7–2.3	>2.3
Ascites	1 None	Mild/controlled	Moderate-severe
Encephalopathy	1 None	Grade I–II	Grade III–IV
Child-Pugh Score	/ 15

Interpretation
Class	Score	1-Year Survival
A | 5–6 | ~100%
B | 7–9 | ~80%
C | 10–15 | ~45%

References
Pugh RN, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60(8):646-649. PMID 4541913. Durand F, Valla D. Assessment of the prognosis of cirrhosis: Child-Pugh versus MELD. J Hepatol. 2005;42(Suppl 1):S100-107. PMID 15777564.