Template:Increased ICP treatment

Increased ICP Treatment

  1. Ensure adequate sedation (prevent gag reflex)
  2. IVF to goal MAP >80 (maintains cerebral perfusion)
  3. Mannitol
    • If SBP>90
      • If SBP>90 in adults use hypertonic saline NaCl 5% 150ml over 10 min
    • Reduces ICP w/in 30min; duration of action of 6-8hr
    • Bolus 20% @ 0.25-1 gm/kg as rapid infusion
    • Monitor I+O to maintain euvolemia
  4. Hyperventilation
    • No longer recommended as prophylactic intervention
      • Hyperventilation to PaCO2 <25 never indicated
    • Brief course only recommended if impending herniation (i.e., Cushing reflex)
        • Maintain PaCO2 28-35 (20 breaths/min)
  5. Seizure
    • Treat immediately
    • Seizure prophylaxis reduces seizures but does not improve long-term outcomes
  6. Goal CPP ~60mmHg
    • If MAP <80, then CPP<60