Template:Increased ICP treatment: Difference between revisions
| Line 4: | Line 4: | ||
#[[Mannitol]] | #[[Mannitol]] | ||
#*If SBP>90 | #*If SBP>90 | ||
#*Reduces ICP w/in 30min; duration of action of 6-8hr | #*Reduces ICP w/in 30min; duration of action of 6-8hr | ||
#*Bolus 20% @ 0.25-1 gm/kg as rapid infusion | #*Bolus 20% @ 0.25-1 gm/kg as rapid infusion | ||
Revision as of 20:06, 11 June 2015
Increased ICP Treatment
- Elevate HOB 30 degrees (or reverse Trendelenburg position)
- IVF to goal MAP >80 (maintains cerebral perfusion)
- Mannitol
- If SBP>90
- Reduces ICP w/in 30min; duration of action of 6-8hr
- Bolus 20% @ 0.25-1 gm/kg as rapid infusion
- Monitor I+O to maintain euvolemia
- Hyperventilation
- No longer recommended as prophylactic intervention
- Hyperventilation to PaCO2 <25 never indicated
- Brief course only recommended if impending herniation (i.e., Cushing reflex)
- Maintain PaCO2 28-35 (20 breaths/min)
- No longer recommended as prophylactic intervention
- Seizure
- Treat immediately
- Seizure prophylaxis reduces seizures but does not improve long-term outcomes
- If need for RSI, consider pretreatment with lidocaine and/or fentanyl
- Also ensure adequate sedation (prevent gag reflex)
- Goal cerebral perfusion pressure (CPP) ~60mmHg
- If MAP <80, then CPP<60
- consider crystalloids or colloids (plasma if INR>1.3)
- phenylephrine 10-100mcg/min, or other pressors prn
- transfuse PRBCs, Hb>7
- If MAP <80, then CPP<60
