Template:Tetanus Antibiotics: Difference between revisions

(Created page with "*Metronidazole 500mg IV (7.5mg/kg) q6hrs OR *Clindamycin 600mg IV (7.5mg/kg) q6hrs ====Penicillin==== *Although once the drug of choice it is now no longer recomm...")
 
(Convert to AntibioticDose with disease=Acute tetanus for SMW linking)
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*[[Metronidazole]] 500mg IV (7.5mg/kg) q6hrs OR
*{{AntibioticDose|disease=Acute tetanus|drug=Metronidazole|dose=500mg IV (7.5mg/kg) q6hrs|context=Active tetanus|population=Adult}} OR
*[[Clindamycin]] 600mg IV (7.5mg/kg) q6hrs
*{{AntibioticDose|disease=Acute tetanus|drug=Clindamycin|dose=600mg IV (7.5mg/kg) q6hrs|context=Active tetanus alt|population=Adult}}


====[[Penicillin]]====
====[[Penicillin]]====
*Although once the drug of choice it is now no longer recommended since it may potentiate the effect of tetanus toxin by inhibiting the GABA receptors<ref>Ganesh Kumar AV. Benzathine penicillin, metronidazole and benzyl penicillin in the treatment of tetanus: a randomized, controlled trial .Ann Trop Med Parasitol. 2004 Jan;98(1):59-63 PMID 15000732</ref>
*Although once the drug of choice it is now no longer recommended since it may potentiate the effect of tetanus toxin by inhibiting the GABA receptors<ref>Ganesh Kumar AV. Benzathine penicillin, metronidazole and benzyl penicillin in the treatment of tetanus: a randomized, controlled trial .Ann Trop Med Parasitol. 2004 Jan;98(1):59-63 PMID 15000732</ref>

Revision as of 01:23, 20 March 2026

Penicillin

  • Although once the drug of choice it is now no longer recommended since it may potentiate the effect of tetanus toxin by inhibiting the GABA receptors[1]
  1. Ganesh Kumar AV. Benzathine penicillin, metronidazole and benzyl penicillin in the treatment of tetanus: a randomized, controlled trial .Ann Trop Med Parasitol. 2004 Jan;98(1):59-63 PMID 15000732