COVID-19 Vaccine (Moderna): Difference between revisions
(Reverted edits by Rossdonaldson1 (talk) to last revision by Jmf300) Tags: Removed redirect Rollback |
|||
| (6 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
==Background== | ==Background== | ||
The Moderna COVID-19 vaccine is an mRNA based vaccine which is approved in the United States to prevent symptomatic COVID-19 infection. The Moderna vaccine was the second COVID-19 vaccine to be approved for distribution in the United States, and it was granted Emergency Use Authorization by the United States Food and Drug Administration on 18 December 2020. | The Moderna COVID-19 vaccine is an mRNA based vaccine which is approved in the United States to prevent symptomatic COVID-19 infection. The Moderna vaccine was the second COVID-19 vaccine to be approved for distribution in the United States, and it was granted Emergency Use Authorization by the United States Food and Drug Administration (FDA) on 18 December 2020. | ||
The approved dosing regimen is two doses, 100 μg each, administered 28 days apart. The vaccine is approved for individuals 18 years of age and older. | The approved dosing regimen is two doses, 100 μg each, administered 28 days apart. The vaccine is approved for individuals 18 years of age and older. | ||
| Line 7: | Line 7: | ||
==Clinical Features== | ==Clinical Features== | ||
==Administration== | ==Administration== | ||
*Type: | *Type: SARS-CoV-2 spike glycoprotein (S) antigen encoded by RNA and formulated in lipid nanoparticles (LNPs). | ||
*Dosage Forms: | *Dosage Forms: 2 doses of 100 μg each, administered 28 days apart. | ||
*Routes of Administration: | *Routes of Administration: Intramuscular | ||
*Common Trade Names: | *Common Trade Names: Moderna COVID-19 Vaccine, Moderna Vaccine | ||
==Adult Dosing== | ==Adult Dosing== | ||
Latest revision as of 22:52, 18 January 2022
Background
The Moderna COVID-19 vaccine is an mRNA based vaccine which is approved in the United States to prevent symptomatic COVID-19 infection. The Moderna vaccine was the second COVID-19 vaccine to be approved for distribution in the United States, and it was granted Emergency Use Authorization by the United States Food and Drug Administration (FDA) on 18 December 2020.
The approved dosing regimen is two doses, 100 μg each, administered 28 days apart. The vaccine is approved for individuals 18 years of age and older.
The vaccine is intended to prevent the COVID-19 illness, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Moderna vaccine targets the SARS-CoV-2 spike glycoprotein (S).
Clinical Features
Administration
- Type: SARS-CoV-2 spike glycoprotein (S) antigen encoded by RNA and formulated in lipid nanoparticles (LNPs).
- Dosage Forms: 2 doses of 100 μg each, administered 28 days apart.
- Routes of Administration: Intramuscular
- Common Trade Names: Moderna COVID-19 Vaccine, Moderna Vaccine
Adult Dosing
Pediatric Dosing
Special Populations
Pregnancy Rating
Lactation risk
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion: