Template:Mastoiditis Antibiotics: Difference between revisions

Latest revision as of 12:58, 20 March 2026

Coverage against S. pneumoniae, S. pyogenes, S. aureus, H. influenzae

Clindamycin 600mg IV q8 hours OR (if MRSA concern use Vancomycin regimen)
Vancomycin 15-20mg/kg IV q12 hours PLUS
- Ceftriaxone 1g (50mg/kg) IV once daily OR
- Ampicillin/Sulbactam 3g (50mg/kg) IV q6 hours
If chronic or severe, need pseudomonas coverage
- Vancomycin + Piperacillin/Tazobactam 100mg/kg/dose piperacillin IV q6h (max 4g piperacillin/dose)

Pediatric

Ceftriaxone 50mg/kg IV daily (max 2g) OR
Ampicillin/Sulbactam 50mg/kg IV q6hrs (max 3g/dose)
If MRSA concern: add Vancomycin 15mg/kg IV q6hrs
If chronic/severe: Piperacillin/Tazobactam 100mg/kg IV q6hrs (max 4.5g/dose) + Vancomycin
Clindamycin 10-13mg/kg IV q8hrs (max 900mg/dose) as alternative

@@ Line 1: / Line 1: @@
 ''Coverage against [[S. pneumoniae]], S. pyogenes, [[S. aureus]], [[H. influenzae]]''
+*{{AntibioticDose|disease=Mastoiditis|drug=Clindamycin|dose=600mg IV q8 hours|context=Empiric}} '''OR''' (if [[MRSA]] concern use [[Vancomycin]] regimen)
+*{{AntibioticDose|disease=Mastoiditis|drug=Vancomycin|dose=15-20mg/kg IV q12 hours|context=Empiric}} '''PLUS'''
+**{{AntibioticDose|disease=Mastoiditis|drug=Ceftriaxone|dose=1g (50mg/kg) IV once daily|context=Empiric}} '''OR'''
+**{{AntibioticDose|disease=Mastoiditis|drug=Ampicillin/Sulbactam|dose=3g (50mg/kg) IV q6 hours|context=Empiric}}
+*If chronic or severe, need pseudomonas coverage
+** [[Vancomycin]] + {{AntibioticDose|disease=Mastoiditis|drug=Piperacillin/Tazobactam|dose=100mg/kg/dose piperacillin IV q6h (max 4g piperacillin/dose)|context=Chronic/Severe}}
-*[[Clindamycin]] 600mg IV q8 hours '''OR''' (if [[MRSA]] concern use [[Vancomycin]] regimen)
+====Pediatric====
-*[[Vancomycin]] 15-20mg/kg IV q12 hours '''PLUS'''
+*{{AntibioticDose|disease=Mastoiditis|drug=Ceftriaxone|dose=50mg/kg IV daily (max 2g)|context=Pediatric Empiric|population=Pediatric}} '''OR'''
-**[[Ceftriaxone]] 1g (50mg/kg) IV once daily '''OR'''
+*{{AntibioticDose|disease=Mastoiditis|drug=Ampicillin/Sulbactam|dose=50mg/kg IV q6hrs (max 3g/dose)|context=Pediatric Empiric|population=Pediatric}}
-**[[Ampicillin/Sulbactam]] 3g (50mg/kg) IV q6 hours
+*If MRSA concern: add {{AntibioticDose|disease=Mastoiditis|drug=Vancomycin|dose=15mg/kg IV q6hrs|context=Pediatric MRSA|population=Pediatric}}
-*If chronic or severe, need pseudomonas coverage
+*If chronic/severe: {{AntibioticDose|disease=Mastoiditis|drug=Piperacillin/Tazobactam|dose=100mg/kg IV q6hrs (max 4.5g/dose)|context=Pediatric Chronic/Severe|population=Pediatric}} + Vancomycin
-** [[Vanco]] + [[Piperacillin-tazobactam]] (Zosyn) 100mg/kg/dose piperacillin IV q6h (max 4g piperacillin/dose)
+*{{AntibioticDose|disease=Mastoiditis|drug=Clindamycin|dose=10-13mg/kg IV q8hrs (max 900mg/dose)|context=Pediatric|population=Pediatric}} as alternative