Polycystic kidney disease: Difference between revisions
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*Hereditary disorder, autosomal dominant | *Hereditary disorder, autosomal dominant | ||
*Accounts for ~2% of new cases of renal failure each year | *Accounts for ~2% of new cases of renal failure each year | ||
===Mortality=== | |||
*Cardiovascular | |||
*Infection, septicemia | |||
*[[Subarachnoid hemorrhage]] | |||
*Uremia | |||
==Clinical Features== | ==Clinical Features== | ||
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**self-limited | **self-limited | ||
**cysts are susceptible to traumatic injury | **cysts are susceptible to traumatic injury | ||
==Differential Diagnosis== | |||
==Evaluation== | ==Evaluation== | ||
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*CBC, BMP | *CBC, BMP | ||
*Urinalysis +/- Urine culture | *Urinalysis +/- Urine culture | ||
==Management== | |||
==Disposition== | |||
==See Also== | |||
==References== | ==References== | ||
Revision as of 14:07, 2 October 2016
Background
- Multisystemic and progressive disorder resulting in renal cysts and renal enlargement
- Hereditary disorder, autosomal dominant
- Accounts for ~2% of new cases of renal failure each year
Mortality
- Cardiovascular
- Infection, septicemia
- Subarachnoid hemorrhage
- Uremia
Clinical Features
- Clinical presentation typically begins in 3rd to 4th decade of life, but may be detectable in childhood
- Abdominal pain, flank pain and/or back pain is most common initial symptom.
- Pain due to:
- enlargement of cysts
- bleeding within cyst or gross hematuria with clots or perinephric hematoma
- urinary tract infection
- nephrolithiasis
- Pain due to:
- Hematuria
- self-limited
- cysts are susceptible to traumatic injury
Differential Diagnosis
Evaluation
- US is the imaging of choice
- CBC, BMP
- Urinalysis +/- Urine culture
Management
Disposition
See Also
References
- Torra R et al. Polycystic Kidney Disease. eMedicine. Feb 11, 2016. http://emedicine.medscape.com/article/244907-overview#showall