Trigeminal neuralgia - Revision history

Danbot: Add peer-reviewed reference

2026-03-22T10:17:44Z

Add peer-reviewed reference

← Older revision		Revision as of 10:17, 22 March 2026
Line 5:		Line 5:

	==Clinical Features==		==Clinical Features==
	*Paroxysms of severe unilateral pain in trigeminal nerve distribution lasting only seconds		*Paroxysms of severe unilateral pain in trigeminal nerve distribution lasting only seconds <ref>Cruccu G, et al. Trigeminal neuralgia. N Engl J Med. 2020;383(8):754-762. PMID 32813951</ref>
	*Normal neuro exam		*Normal neuro exam
	*No pain between paroxysms		*No pain between paroxysms

2022-08-07T11:31:49Z

Management

← Older revision		Revision as of 11:31, 7 August 2022
Line 22:		Line 22:

	==Management==		==Management==
	~~===[[Phenytoin]]===~~
	*250mg IV to abort an acute attack
	*Relief lasts from four hours to three days
	*[[Fosphenytoin]] seems to work similarly

	===[[Carbamazepine]]===		===[[Carbamazepine]]===

2021-01-27T18:41:47Z

← Older revision		Revision as of 18:41, 27 January 2021
Line 1:		Line 1:
	==Background==		==Background==
	[[File:Gray778.png\|thumb\|Trigeminal nerve.]]		[[File:Gray778.png\|thumb\|Trigeminal nerve anatomy.]]
	[[File:Gray784.png\|thumb\|Dermatome distribution of the trigeminal nerve: V1 (green), V2 (red), and V3 (yellow).]]		[[File:Gray784.png\|thumb\|Dermatome distribution of the trigeminal nerve: V1 (green), V2 (red), and V3 (yellow).]]
	*Also known as tic doulourex		*Also known as tic doulourex

2021-01-27T18:33:59Z

← Older revision		Revision as of 18:33, 27 January 2021
Line 1:		Line 1:
	==Background==		==Background==
			[[File:Gray778.png\|thumb\|Trigeminal nerve.]]
			[[File:Gray784.png\|thumb\|Dermatome distribution of the trigeminal nerve: V1 (green), V2 (red), and V3 (yellow).]]
	*Also known as tic doulourex		*Also known as tic doulourex

2021-01-03T00:27:30Z

Background

2021-01-03T00:27:10Z

Background

2020-02-25T23:14:45Z

Carbamazepine

← Older revision		Revision as of 23:14, 25 February 2020
Line 30:		Line 30:
	*Increase by 100-200mg every 3 days		*Increase by 100-200mg every 3 days
	*Usual maintenance dose is 400-800mg (rare >1500mg)		*Usual maintenance dose is 400-800mg (rare >1500mg)
			*Metabolized by liver (cytochrome P450)
			**LFTs monitored on outpatient basis
	*Pain relief occurs within several hours to days (94% within 48 hours)		*Pain relief occurs within several hours to days (94% within 48 hours)
	*Target serum concentration is 24-43 μmol/L		*Target serum concentration is 24-43 μmol/L

2019-10-03T16:47:36Z

Other agents

← Older revision		Revision as of 16:47, 3 October 2019
Line 35:		Line 35:

	===Other agents===		===Other agents===
	*[[Baclofen]], [[clonazepam]], [[valproic acid]], [[lamotrigine]], [[gabapentin]], ~~Oxcarbazepine~~, [[topiramate]]		*[[Baclofen]], [[clonazepam]], [[valproic acid]], [[lamotrigine]], [[gabapentin]], [[oxcarbazepine]], [[topiramate]]

	===Surgery===		===Surgery===

2019-10-02T00:27:17Z

Evaluation

← Older revision		Revision as of 00:27, 2 October 2019
Line 15:		Line 15:
	==Evaluation==		==Evaluation==
	*Sensory loss, bilateral involvement, and younger age (<40) are associated with a higher risk of secondary TN, but their absence does not rule out secondary TN		*Sensory loss, bilateral involvement, and younger age (<40) are associated with a higher risk of secondary TN, but their absence does not rule out secondary TN
	*Consider CT/MRI in these patients to rule out structural etiology		*Consider [[head CT\|CT]]/[[brain MRI\|MRI]] in these patients to rule out structural etiology
	*<5% of patients have V1 distribution, examine carefully for [[zoster]] in these patients		*<5% of patients have V1 distribution, examine carefully for [[zoster]] in these patients

2019-08-19T17:53:01Z

Other agents

← Older revision		Revision as of 17:53, 19 August 2019
Line 35:		Line 35:

	===Other agents===		===Other agents===
	*[[Baclofen]], clonazepam, [[valproic acid]], [[lamotrigine]], [[gabapentin]], Oxcarbazepine, [[topiramate]]		*[[Baclofen]], [[clonazepam]], [[valproic acid]], [[lamotrigine]], [[gabapentin]], Oxcarbazepine, [[topiramate]]

	===Surgery===		===Surgery===