Thrombocytopenia - Revision history

Rossdonaldson1: /* Clinical Features */

2023-06-07T22:03:32Z

Clinical Features

← Older revision		Revision as of 22:03, 7 June 2023
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	==Clinical Features==		==Clinical Features==
	[[File:PMC4192833 TODENTJ-8-164 F1.png\|thumb\|Unprovoked gingival bleeding.]]		[[File:PMC4192833 TODENTJ-8-164 F1.png\|thumb\|Unprovoked gingival bleeding.]]
			[[File:Purpura.jpg\|thumb\|Petechiae in a patient with thrombocytopenia.]]
			[[File:Petechia on the tongue.jpg\|thumb\|Petechiae on the tongue in a patient with thrombocytopenia.]]
			[[File:Petechia lower leg2.jpg\|thumb\|Petechiae on the lower leg in a patient with thrombocytopenia.]]
	*Nonpalpable [[petechiae]]/purpura		*Nonpalpable [[petechiae]]/purpura
	*Mucosal bleeding (gingival, [[epistaxis]])		*Mucosal bleeding (gingival, [[epistaxis]])

2023-06-07T22:02:35Z

Clinical Features

← Older revision		Revision as of 22:02, 7 June 2023
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	==Clinical Features==		==Clinical Features==
			[[File:PMC4192833 TODENTJ-8-164 F1.png\|thumb\|Unprovoked gingival bleeding.]]
	*Nonpalpable [[petechiae]]/purpura		*Nonpalpable [[petechiae]]/purpura
	*Mucosal bleeding (gingival, [[epistaxis]])		*Mucosal bleeding (gingival, [[epistaxis]])

2021-02-21T02:35:35Z

Clinical Features

← Older revision		Revision as of 02:35, 21 February 2021
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	*Mucosal bleeding (gingival, [[epistaxis]])		*Mucosal bleeding (gingival, [[epistaxis]])
	*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]		*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]
	*Deep tissue/joint bleeding is less common (more likely due to [[Coagulopathy (main)\|coagulopathies)		*Deep tissue/joint bleeding is less common (more likely due to [[Coagulopathy (main)\|coagulopathies]])

	==Differential Diagnosis==		==Differential Diagnosis==

2021-02-21T02:35:08Z

Clinical Features

← Older revision		Revision as of 02:35, 21 February 2021
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	*Mucosal bleeding (gingival, [[epistaxis]])		*Mucosal bleeding (gingival, [[epistaxis]])
	*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]		*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]
	*Deep tissue/joint bleeding is less common (more likely due to coagulopathies)		*Deep tissue/joint bleeding is less common (more likely due to [[Coagulopathy (main)\|coagulopathies)

	==Differential Diagnosis==		==Differential Diagnosis==

2019-10-01T18:49:27Z

← Older revision		Revision as of 18:49, 1 October 2019
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	==Clinical Features==		==Clinical Features==
	*Nonpalpable [[petechiae]]/purpura		*Nonpalpable [[petechiae]]/purpura
	*Mucosal bleeding (gingival, epistaxis)		*Mucosal bleeding (gingival, [[epistaxis]])
	*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]		*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]
	*Deep tissue/joint bleeding is less common (more likely due to coagulopathies)		*Deep tissue/joint bleeding is less common (more likely due to coagulopathies)
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	==Management==		==Management==
	Patient treatments are stratified by the presence or ~~[[abscess]]~~ of bleeding and in the non bleeding patient by the platelet number and the presumed cause of the thrombocytopenia		Patient treatments are stratified by the presence or absence of bleeding and in the non bleeding patient by the platelet number and the presumed cause of the thrombocytopenia

	{{Platelet transfusion indications}}		{{Platelet transfusion indications}}

2019-10-01T18:48:55Z

← Older revision		Revision as of 18:48, 1 October 2019
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	*Nonpalpable [[petechiae]]/purpura		*Nonpalpable [[petechiae]]/purpura
	*Mucosal bleeding (gingival, epistaxis)		*Mucosal bleeding (gingival, epistaxis)
	*Menorrhagia, hemoptysis, hematuria, hematochezia		*[[Vaginal Bleed Non-Pregnant\|Menorrhagia]], [[hemoptysis]], [[hematuria]], [[rectal bleeding\|hematochezia]]
	*Deep tissue/joint bleeding is less common (more likely due to coagulopathies)		*Deep tissue/joint bleeding is less common (more likely due to coagulopathies)

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	[[File:Thrombocytopenia Evaluation.png\|thumb\|Algorithm for the Evaluation of Thrombocytopenia]]		[[File:Thrombocytopenia Evaluation.png\|thumb\|Algorithm for the Evaluation of Thrombocytopenia]]
	*Platelet count (CBC)		*Platelet count (CBC)
			*Additional workup per clinical presentation

	==Management==		==Management==
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	===Transfusion contraindications===		===Transfusion contraindications===
	*TTP, DIC, HIT		*[[TTP]], [[DIC]], [[HIT]]

	===Pediatrics===		===Pediatrics===
	*1 unit of platelets per 5kg body weight raises count by 50k		*1 unit of [[platelets]] per 5kg body weight raises count by 50k

	==Disposition==		==Disposition==

2018-09-08T17:41:01Z

Evaluation

← Older revision		Revision as of 17:41, 8 September 2018
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	==Evaluation==		==Evaluation==
			[[File:Thrombocytopenia Evaluation.png\|thumb\|Algorithm for the Evaluation of Thrombocytopenia]]
	*Platelet count (CBC)		*Platelet count (CBC)

2018-09-08T17:40:21Z

Differential Diagnosis

← Older revision		Revision as of 17:40, 8 September 2018
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	==Differential Diagnosis==		==Differential Diagnosis==
			[[File:Thrombocytopenia.png\|thumb\|Differential Diagnosis of Thrombocytopenia]]
	{{Thrombocytopenia}}		{{Thrombocytopenia}}
	{{Increased bleeding DDX}}		{{Increased bleeding DDX}}

2017-04-13T22:34:03Z

Background

← Older revision		Revision as of 22:34, 13 April 2017
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	==Background==		==Background==
	*Thrombocytopenia is ~~define~~ as platelets of less than 150 x 10<sup>3</sup>/mcL. Symptoms such as bruising and petechiae usually occur at counts at 50 x 10<sup>3</sup>/mcL and between 5-10x 10<sup>3</sup>/mcL there is a high risk of spontaneous bleeding.		*Thrombocytopenia is defined as platelets of less than 150 x 10<sup>3</sup>/mcL. Symptoms such as bruising and petechiae usually occur at counts at 50 x 10<sup>3</sup>/mcL and between 5-10x 10<sup>3</sup>/mcL there is a high risk of spontaneous bleeding.

	==Clinical Features==		==Clinical Features==

2017-03-10T08:09:08Z

Text replacement - "abscess " to "abscess "

← Older revision		Revision as of 08:09, 10 March 2017
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	==Management==		==Management==
	Patient treatments are stratified by the presence or abscess of bleeding and in the non bleeding patient by the platelet number and the presumed cause of the thrombocytopenia		Patient treatments are stratified by the presence or [[abscess]] of bleeding and in the non bleeding patient by the platelet number and the presumed cause of the thrombocytopenia

	{{Platelet transfusion indications}}		{{Platelet transfusion indications}}