Seizure (peds) - Revision history

Danbot: Add MedicationDose entries (dextrose, hypertonic saline, calcium gluconate, pyridoxine) with SMW annotations

2026-03-20T18:49:11Z

Add MedicationDose entries (dextrose, hypertonic saline, calcium gluconate, pyridoxine) with SMW annotations

← Older revision		Revision as of 18:49, 20 March 2026
Line 97:		Line 97:

	{{Pediatric anticonvulsants}}		{{Pediatric anticonvulsants}}


			==Medication Dosing==
			{{MedicationDose
			\| drug = Dextrose
			\| dose = 2mL/kg of D25W
			\| route = IV
			\| context = Hypoglycemic seizure (glucose <50mg/dL)
			\| indication = Seizure (peds)
			\| population = Pediatric
			}}
			{{MedicationDose
			\| drug = Hypertonic saline
			\| dose = 4-6mL/kg of 3% NaCl over 20min
			\| route = IV
			\| context = Hyponatremic seizure
			\| indication = Seizure (peds)
			\| population = Pediatric
			}}
			{{MedicationDose
			\| drug = Calcium gluconate
			\| dose = 0.3mL/kg of 10% solution over 5-10min
			\| route = IV
			\| context = Hypocalcemic seizure
			\| indication = Seizure (peds)
			\| population = Pediatric
			}}
			{{MedicationDose
			\| drug = Pyridoxine
			\| dose = 100mg
			\| route = IV
			\| context = Pyridoxine-responsive seizure disorder
			\| indication = Seizure (peds)
			\| population = Pediatric
			}}

	==Disposition==		==Disposition==

2026-01-17T17:16:52Z

2026-01-17T17:14:12Z

2023-10-28T16:18:17Z

Neonatal Seizure

← Older revision		Revision as of 16:18, 28 October 2023
Line 33:		Line 33:
	*Treatment		*Treatment
	**Start IV [[pediatric antibiotics\|antimicrobials]] (including [[acyclovir]])		**Start IV [[pediatric antibiotics\|antimicrobials]] (including [[acyclovir]])
	**Consider [[pyridoxine]] and [[folic acid]] if unresponsive to ~~benzos~~<ref>Robert Surtees and Nicole Wolf. Treatable neonatal epilepsy. Arch Dis Child. 2007 Aug; 92(8): 659–661.</ref>		**Phenobarbital is first-line treatment for most neonatal seizures <ref> Shellhaas, R. Treatment of neonatal seizures. In: UpToDate, Post TW (Ed), Wolters Kluwer. https://www.uptodate.com (Accessed on October 28, 2023.) </ref>
			**Consider [[pyridoxine]] and [[folic acid]] if unresponsive to treatment<ref>Robert Surtees and Nicole Wolf. Treatable neonatal epilepsy. Arch Dis Child. 2007 Aug; 92(8): 659–661.</ref>
	***Pyridoxal phosphate 10mg/kg/dose q2h x 2 doses		***Pyridoxal phosphate 10mg/kg/dose q2h x 2 doses
	***If persistent, folinic acid 5mg q6h x 2 doses		***If persistent, folinic acid 5mg q6h x 2 doses

2022-10-19T21:07:54Z

2022-10-19T21:00:04Z

Background

2022-10-19T20:56:46Z

Other

← Older revision		Revision as of 20:56, 19 October 2022
Line 96:		Line 96:
	*Consider [[Pyridoxine]] (vitamin B6) 1g per g of [[INH]] ingested (in D5W IV over 30 min) <ref> Minns AB, Ghafouri N, Clark RF. Isoniazid-induced status epilepticus in a pediatric patient after inadequate pyridoxine therapy. Pediatr Emerg Care. 2010; 26(5):380-1. </ref>		*Consider [[Pyridoxine]] (vitamin B6) 1g per g of [[INH]] ingested (in D5W IV over 30 min) <ref> Minns AB, Ghafouri N, Clark RF. Isoniazid-induced status epilepticus in a pediatric patient after inadequate pyridoxine therapy. Pediatr Emerg Care. 2010; 26(5):380-1. </ref>
	*Consider Pyridoxine Responsive Seizure Disorder - 100mg/pyridoxine is generally effective <ref>Pyridoxine dependent seizures a wider clinical spectrum. Archives of Disease in Childhood.1983 (58) 415-418. http://adc.bmj.com/content/58/6/415.full.pdf</ref>		*Consider Pyridoxine Responsive Seizure Disorder - 100mg/pyridoxine is generally effective <ref>Pyridoxine dependent seizures a wider clinical spectrum. Archives of Disease in Childhood.1983 (58) 415-418. http://adc.bmj.com/content/58/6/415.full.pdf</ref>

			{{Pediatric anticonvulsants}}

	==Disposition==		==Disposition==

2021-03-11T23:49:02Z

Acute Management (status epilepticus)

2021-03-11T21:20:44Z

Management

← Older revision		Revision as of 21:20, 11 March 2021
Line 72:		Line 72:
	**If paralytic used, EEG monitoring should be arranged		**If paralytic used, EEG monitoring should be arranged

	==Management==		==Acute Management (status epilepticus)==
	===1st Line===		===1st Line===
	{\| cellspacing="1" cellpadding="3" border="0" bgcolor="#666666" style="color: rgb(51, 51, 51); font-family: Verdana,Arial,Helvetica,sans-serif; width: 522px; height: 339px;"		{\| cellspacing="1" cellpadding="3" border="0" bgcolor="#666666" style="color: rgb(51, 51, 51); font-family: Verdana,Arial,Helvetica,sans-serif; width: 522px; height: 339px;"

2021-03-11T21:16:18Z

← Older revision		Revision as of 21:16, 11 March 2021
Line 1:		Line 1:
	~~''This page refers to pediatric patients; see~~ [[seizure]] ~~for adult patients~~.''		{{Peds top}} [[seizure]].''
	==Background==		==Background==

← Older revision		Revision as of 21:07, 19 October 2022
Line 109:		Line 109:
	*[[Febrile Seizure]]		*[[Febrile Seizure]]
	*[[Seizure Levels and Reloading]]		*[[Seizure Levels and Reloading]]
			*[[Status epilepticus (peds)]]

	==External Links==		==External Links==