Penicillin V - Revision history

Danbot: Add AntibioticDose SMW query table for dynamic indications by disease

2026-03-20T20:38:30Z

Add AntibioticDose SMW query table for dynamic indications by disease

@@ Line 26: / Line 26: @@
 ===Prosthetic Joint Infection, Chronic Suppression (Off-Label)<ref>Osmon DR, Berbari EF, Berendt AR, et al, “Diagnosis and Management of Prosthetic Joint Infection: Clinical Practice Guideline by the Infectious Diseases Society of America,” Clin Infect Dis, 2013, 56(1):e1-25. PubMed 23223583</ref>===
 *500mg BID-QID
 ==Pediatric Dosing==
 ===General===
 *'''<12 years'''

Rossdonaldson1: /* Strep PharyngitisShulman ST, Bisno AL, Clegg HW, et al; Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10):e86-102. PubMed 22965026 */

2026-01-28T18:09:07Z

Strep PharyngitisShulman ST, Bisno AL, Clegg HW, et al; Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10):e86-102. PubMed 22965026

← Older revision		Revision as of 18:09, 28 January 2026
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	==Adult Dosing==		==Adult Dosing==
	===[[Strep Pharyngitis]]<ref>Shulman ST, Bisno AL, Clegg HW, et al; Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10):e86-102. PubMed 22965026</ref>===		===[[Strep Pharyngitis]]===
	*Acute		*Acute
	**250mg QID or 500mg BID x 10 days		**250mg QID or 500mg BID x 10 days<ref>Shulman ST, Bisno AL, Clegg HW, et al; Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10):e86-102. PubMed 22965026</ref><ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>
	*Chronic carrier (Group A)		*Chronic carrier (Group A)
	**500mg QID x 10 days + rifampin		**500mg QID x 10 days + rifampin<ref>Shulman ST, Bisno AL, Clegg HW, et al; Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10):e86-102. PubMed 22965026</ref>
	**Max: 2000mg/day		**Max: 2000mg/day

Ostermayer at 17:32, 18 July 2025

2025-07-18T17:32:59Z

← Older revision		Revision as of 17:32, 18 July 2025
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	==General==		==General==
	*Type: Natural [[Is DrugClass::Penicillin]]		*Type: [[Is PenicillinType::Natural]] [[Is DrugClass::Penicillin]]
	*Dosage Forms: PO 250mg, 500mg; 125mg/5mL, 250mg/5 mL		*Dosage Forms: PO 250mg, 500mg; 125mg/5mL, 250mg/5 mL
	*Common Trade Names:		*Common Trade Names:

Ostermayer at 17:28, 18 July 2025

2025-07-18T17:28:58Z

← Older revision		Revision as of 17:28, 18 July 2025
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	==General==		==General==
	*Type: Natural [[Penicillin]]		*Type: Natural [[Is DrugClass::Penicillin]]
	*Dosage Forms: PO 250mg, 500mg; 125mg/5mL, 250mg/5 mL		*Dosage Forms: PO 250mg, 500mg; 125mg/5mL, 250mg/5 mL
	*Common Trade Names:		*Common Trade Names:

ClaireLewis at 21:29, 23 September 2019

2019-09-23T21:29:01Z

← Older revision		Revision as of 21:29, 23 September 2019
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
			*Anaphylaxis
			*Interstitial nephritis
			*Seizures
	===Common===		===Common===
			*Nausea, diarrhea
			*Oral candidiasis
			*Anemia
			*Positive Coombs reaction

	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: 0.5-0.6hr
	*Metabolism:		*Metabolism: Hepatic
	*Excretion:		*Excretion: urinary
	*Mechanism of Action:		*Mechanism of Action: Inhibits the biosynthesis of cell wall mucopeptide

	==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==		==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==
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	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:ID]]

Mholtz at 06:42, 13 July 2017

2017-07-13T06:42:29Z

← Older revision		Revision as of 06:42, 13 July 2017
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	==References==		==References==
			<references/>

	~~<references/>~~
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-21T05:24:27Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 05:24, 21 July 2016
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	==General==		==General==
	*Type: Natural [[Penicillin]]		*Type: Natural [[Penicillin]]
	*Dosage Forms: PO 250mg, 500mg; 125mg/5mL, ~~250 mg~~/5 mL		*Dosage Forms: PO 250mg, 500mg; 125mg/5mL, 250mg/5 mL
	*Common Trade Names:		*Common Trade Names:

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	*Chronic carrier (Group A)		*Chronic carrier (Group A)
	**500mg QID x 10 days + rifampin		**500mg QID x 10 days + rifampin
	**Max: ~~2000 mg~~/day		**Max: 2000mg/day

	===Actinomycosis===		===Actinomycosis===
Line 16:		Line 16:
	**2000-4000mg PO divided q6 hours x 8 weeks		**2000-4000mg PO divided q6 hours x 8 weeks
	*Surgical		*Surgical
	**I.V. [[Penicillin G]] x 4-6 weeks, then 2000-~~4000 mg~~ PO divided q6h x 6-12 months		**I.V. [[Penicillin G]] x 4-6 weeks, then 2000-4000mg PO divided q6h x 6-12 months

	===[[Erysipelas]]===		===[[Erysipelas]]===
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	===General===		===General===
	*'''<12 years'''		*'''<12 years'''
	**25-~~50 mg~~/kg/day divided q6-8 hours		**25-50mg/kg/day divided q6-8 hours
	**Max: ~~2000 mg~~/day		**Max: 2000mg/day
	*≥12 years		*≥12 years
	**125-500mg q6-8 hours		**125-500mg q6-8 hours
	**Alt: 25-~~50 mg~~/kg/day divided q6-8 hours		**Alt: 25-50mg/kg/day divided q6-8 hours
	**Max: ~~2000 mg~~/day		**Max: 2000mg/day

	===[[Strep Pharyngitis]]===		===[[Strep Pharyngitis]]===
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	**>27kg: 500mg BID-TID x 10 days		**>27kg: 500mg BID-TID x 10 days
	*Chronic Carrier ([[Group A streptococci]]		*Chronic Carrier ([[Group A streptococci]]
	**~~50 mg~~/kg/day divided q6 hours x 10 days + [[rifampin]]		**50mg/kg/day divided q6 hours x 10 days + [[rifampin]]
	**Max: ~~2000 mg~~/day<ref>Shulman, 2012</ref>		**Max: 2000mg/day<ref>Shulman, 2012</ref>
	*Recurrent Rheumatic Fever, prophylaxis		*Recurrent Rheumatic Fever, prophylaxis
	**250mg BID<ref>4.Gerber MA, Baltimore RS, Eaton CB, et al, "Prevention of Rheumatic Fever and Diagnosis and Treatment of Acute Streptococcal pharyngitis: A Scientific Statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: Endorsed by the American Academy of Pediatrics," Circulation, 2009, 119(11):1541-51. PubMed 19246689</ref>		**250mg BID<ref>4.Gerber MA, Baltimore RS, Eaton CB, et al, "Prevention of Rheumatic Fever and Diagnosis and Treatment of Acute Streptococcal pharyngitis: A Scientific Statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: Endorsed by the American Academy of Pediatrics," Circulation, 2009, 119(11):1541-51. PubMed 19246689</ref>

	===[[Anthrax]] (Cutaneous)===		===[[Anthrax]] (Cutaneous)===
	*25-~~50 mg~~/kg/day divided BID-QID		*25-50mg/kg/day divided BID-QID
	*Max: 500mg per dose (Stevens, 2005)		*Max: 500mg per dose (Stevens, 2005)

	===[[Pneumonia]], Community-Acquired (>3 Months)<ref>Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53(7):e25-76. [PubMed 21880587]</ref>===		===[[Pneumonia]], Community-Acquired (>3 Months)<ref>Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53(7):e25-76. [PubMed 21880587]</ref>===
	*50-75mg/kg/day divided q6-8h hours		*50-75mg/kg/day divided q6-8h hours
	*Max: ~~2000 mg~~/day		*Max: 2000mg/day

	==Special Populations==		==Special Populations==

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-20T03:14:51Z

Text replacement - "5 mg" to "5mg"

← Older revision		Revision as of 03:14, 20 July 2016
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	===[[Pneumonia]], Community-Acquired (>3 Months)<ref>Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53(7):e25-76. [PubMed 21880587]</ref>===		===[[Pneumonia]], Community-Acquired (>3 Months)<ref>Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53(7):e25-76. [PubMed 21880587]</ref>===
	*50-~~75 mg~~/kg/day divided q6-8h hours		*50-75mg/kg/day divided q6-8h hours
	*Max: 2000 mg/day		*Max: 2000 mg/day

Ostermayer: Text replacement - "Category:Drugs" to "Category:Pharmacology"

2016-03-22T15:54:14Z

Text replacement - "Category:Drugs" to "Category:Pharmacology"

← Older revision		Revision as of 15:54, 22 March 2016
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	<references/>		<references/>
	[[Category:~~Drugs~~]]		[[Category:Pharmacology]]

Rossdonaldson1: /* Source */

2016-01-30T00:41:04Z

Source

← Older revision		Revision as of 00:41, 30 January 2016
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	*[[Antibiotics (Main)]]		*[[Antibiotics (Main)]]

	==~~Source~~==		==References==

	<references/>		<references/>
	[[Category:Drugs]]		[[Category:Drugs]]