Intrathecal drug delivery system complications - Revision history

Rossdonaldson1: /* See Also */

2025-11-05T16:37:08Z

2021-03-11T17:28:00Z

← Older revision	Revision as of 17:28, 11 March 2021
(No difference)

2019-10-28T16:37:36Z

Differential Diagnosis

← Older revision		Revision as of 16:37, 28 October 2019
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	**[[Opioid toxicity]]		**[[Opioid toxicity]]
	**[[Clonidine toxicity]]		**[[Clonidine toxicity]]
	**[[Local anesthetic toxicity]]		**[[Local anesthetic systemic toxicity]]
	**[[Baclofen toxicity]]		**[[Baclofen toxicity]]
	**[[Respiratory failure\|Respiratory depression]] is feared effect of most		**[[Respiratory failure\|Respiratory depression]] is feared effect of most

2019-10-03T03:40:15Z

Management

← Older revision		Revision as of 03:40, 3 October 2019
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	*The device is not removed in an overdose but should be turned off.		*The device is not removed in an overdose but should be turned off.
	*Insertion of a 22-guage needle into the pump reservoir can remove all medication in case device cannot be turned off		*Insertion of a 22-guage needle into the pump reservoir can remove all medication in case device cannot be turned off
	*Consider naloxone to reverse effects taking into account patients chronicity of treatment if they withdrawal		*Consider [[naloxone]] to reverse opioid effects taking into account patients chronicity of treatment if they withdrawal
			*Treat infection aggressively with [[antibiotics]]
			**May be treated without device removal with combination of IV and intrathecal antibiotics<ref>Aristedis R, Dimitrios P, Nikolaos P, Alexandros B. Intrathecal baclofen pump infection treated by adjunct intrareservoir teicoplanin instillation. Surg Neurol Int. 2017;8:38.</ref>, but consult ID and/or anesthesia/appropriate surgical specialty as device may need to be removed

	==Disposition==		==Disposition==

2019-10-03T03:36:15Z

Differential Diagnosis

← Older revision		Revision as of 03:36, 3 October 2019
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	==Differential Diagnosis==		==Differential Diagnosis==
	Complications:		Complications:
	#Respiratory depression ~~from medication overdose~~		*Overdose of medication, see:
	#Infection		**[[Opioid toxicity]]
			**[[Clonidine toxicity]]
			**[[Local anesthetic toxicity]]
			**[[Baclofen toxicity]]
			**[[Respiratory failure\|Respiratory depression]] is feared effect of most
			*[[Infection]]
			**Local [[cellulitis]]
			**[[Meningitis]]

	==Evaluation==		==Evaluation==

2016-10-23T23:27:50Z

← Older revision		Revision as of 23:27, 23 October 2016
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	==Background==		==Background==
	*~~used~~ for delivery of short or long acting pain medications into the thecal space		*Used for delivery of short or long acting pain or anti-spasmodic medications into the thecal space
			*Allows for smaller doses and fewer systemic side effects
	*Most common Intrathecal medications		*Most common Intrathecal medications
	**[[Clonidine]]		**[[Clonidine]]

2016-10-01T02:41:14Z

Background

← Older revision		Revision as of 02:41, 1 October 2016
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	==Background==		==Background==
	*used for delivery of short or long acting pain medications into the ~~theca~~ space		*used for delivery of short or long acting pain medications into the thecal space
	*Most common Intrathecal medications		*Most common Intrathecal medications
	**[[Clonidine]]		**[[Clonidine]]

2016-07-22T07:31:58Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-03-22T16:18:38Z

Text replacement - "Category:Surg" to "Category:Surgery"

2016-03-22T14:14:08Z

Text replacement - "Category:Neuro" to "Category:Neurology"

← Older revision		Revision as of 16:37, 5 November 2025
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	==See Also==		==See Also==
	*[[Medical device complications]]		*[[Medical device complications]]
			*[[Baclofen toxicity]]

	==External Links==		==External Links==