Crotalidae polyvalent immune Fab (Crofab) - Revision history

Athorne: /* See Also */

2021-08-02T21:17:26Z

Athorne: /* See Also */

2021-08-02T20:59:24Z

ClaireLewis at 18:42, 20 September 2019

2019-09-20T18:42:04Z

← Older revision		Revision as of 18:42, 20 September 2019
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	**Cottonmouth (Agkistrodon piscivorus)		**Cottonmouth (Agkistrodon piscivorus)
	*The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.		*The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.

	~~==Administration==~~
	*Type:
	*Dosage Forms:
	*Routes of Administration:
	*Common Trade Names:

	==Indications for Administration of CroFab<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>==		==Indications for Administration of CroFab<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>==

ClaireLewis at 18:03, 20 September 2019

2019-09-20T18:03:58Z

← Older revision		Revision as of 18:03, 20 September 2019
Line 10:		Line 10:
	**Cottonmouth (Agkistrodon piscivorus)		**Cottonmouth (Agkistrodon piscivorus)
	*The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.		*The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.

			==Administration==
			*Type:
			*Dosage Forms:
			*Routes of Administration:
			*Common Trade Names:

	==Indications for Administration of CroFab<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>==		==Indications for Administration of CroFab<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>==
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	==Dosing and Administration==		==Dosing and Administration==
	{{Crofab dosing}}		{{Crofab dosing}}

			Pregnancy category C

	==See Also==		==See Also==

Mholtz at 04:36, 6 July 2017

2017-07-06T04:36:06Z

← Older revision		Revision as of 04:36, 6 July 2017
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	==Synthesis and Production==		==Synthesis and Production==
	~~Crotalidae polyvalent immune Fab (Crofab) is produced~~ from sheep serum after inoculation with venom from:		*Produced from sheep serum after inoculation with venom from:
	*Eastern diamondback rattlesnake (Crotalus adamants)		**Eastern diamondback rattlesnake (Crotalus adamants)
	*Western diamondback rattlesnake (Crotalus atria)		**Western diamondback rattlesnake (Crotalus atria)
	*Mojave rattlesnake (Crotalus scutulatus).		**Mojave rattlesnake (Crotalus scutulatus).
	*Cottonmouth (Agkistrodon piscivorus)		**Cottonmouth (Agkistrodon piscivorus)
	The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.		*The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.

	==Indications for Administration of CroFab==		==Indications for Administration of CroFab<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>==
	~~The following are criteria for administration after Crotalidae bite~~<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>
	*Progression of swelling		*Progression of swelling
	*Abnormal results on lab tests (platelets < 100,000 or fibrinogen < 100)		*Abnormal results on lab tests (platelets < 100,000 or fibrinogen < 100)
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	*[[Crotaline (Pit Vipers)]]		*[[Crotaline (Pit Vipers)]]
	*[[Elapidae (Coral Snakes)]]		*[[Elapidae (Coral Snakes)]]

	==References==		==References==
	<references/>		<references/>

Rossdonaldson1: Text replacement - "AMS" to "altered mental status"

2016-07-31T06:48:51Z

Text replacement - "AMS" to "altered mental status"

← Older revision		Revision as of 06:48, 31 July 2016
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	*Progression of swelling		*Progression of swelling
	*Abnormal results on lab tests (platelets < 100,000 or fibrinogen < 100)		*Abnormal results on lab tests (platelets < 100,000 or fibrinogen < 100)
	*Systemic manifestations (unstable vitals or [[~~AMS~~]])		*Systemic manifestations (unstable vitals or [[altered mental status]])

	==Dosing and Administration==		==Dosing and Administration==

Rossdonaldson1: /* Indications for Administration of CroFab */

2016-07-22T04:32:34Z

Indications for Administration of CroFab

← Older revision		Revision as of 04:32, 22 July 2016
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	==Indications for Administration of CroFab==		==Indications for Administration of CroFab==
			The following are criteria for administration after Crotalidae bite<ref>Dart RC et al. Efficacy of post envenomation administration of antivenin. Toxicon. 1988;26:1218–1221.</ref>
	The following are criteria for administration after Crotalidae bite ~~[3]~~

	*Progression of swelling		*Progression of swelling
	*Abnormal results on lab tests (~~plt~~ < 100,000 or fibrinogen < 100)		*Abnormal results on lab tests (platelets < 100,000 or fibrinogen < 100)
	*Systemic manifestations (unstable vitals or AMS)		*Systemic manifestations (unstable vitals or [[AMS]])

	==Dosing and Administration==		==Dosing and Administration==

Dtanen: update

2016-07-20T22:52:10Z

update

← Older revision		Revision as of 22:52, 20 July 2016
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	The following are criteria for administration after Crotalidae bite [3]		The following are criteria for administration after Crotalidae bite [3]

	Progression of swelling		*Progression of swelling
	Abnormal results on lab tests (plt < 100,000 or fibrinogen < 100)		*Abnormal results on lab tests (plt < 100,000 or fibrinogen < 100)
	Systemic manifestations (unstable vitals or AMS)		*Systemic manifestations (unstable vitals or AMS)

	==Dosing and Administration==		==Dosing and Administration==

Dtanen: update

2016-07-20T22:51:19Z

update

← Older revision		Revision as of 22:51, 20 July 2016
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	Abnormal results on lab tests (plt < 100,000 or fibrinogen < 100)		Abnormal results on lab tests (plt < 100,000 or fibrinogen < 100)
	Systemic manifestations (unstable vitals or AMS)		Systemic manifestations (unstable vitals or AMS)
	~~Neuromuscular toxicity~~

	==Dosing and Administration==		==Dosing and Administration==

Dtanen: update

2016-07-20T22:50:34Z

update

← Older revision		Revision as of 22:50, 20 July 2016
Line 10:		Line 10:
	*Cottonmouth (Agkistrodon piscivorus)		*Cottonmouth (Agkistrodon piscivorus)
	The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.		The Fc portion of the antibody is eliminated after mixture with papain and subsequent purification.

			==Indications for Administration of CroFab==

	The following are criteria for administration after Crotalidae bite [3]		The following are criteria for administration after Crotalidae bite [3]

← Older revision		Revision as of 21:17, 2 August 2021
Line 22:		Line 22:

	==See Also==		==See Also==
	[[Anavip]]		*[[Anavip]]
	*[[Snake bites]]		*[[Snake bites]]
	*[[Crotaline (Pit Vipers)]]		*[[Crotaline (Pit Vipers)]]

← Older revision		Revision as of 20:59, 2 August 2021
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	==See Also==		==See Also==
			[[Anavip]]
	*[[Snake bites]]		*[[Snake bites]]
	*[[Crotaline (Pit Vipers)]]		*[[Crotaline (Pit Vipers)]]