Acute myeloid leukemia - Revision history

ClaireLewis at 23:22, 30 September 2019

2019-09-30T23:22:34Z

← Older revision		Revision as of 23:22, 30 September 2019
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	==Clinical Features==		==Clinical Features==
	*Presents with symptoms of:		*Presents with symptoms of:
	**[[Anemia]]: [[weakness]], easy fatigability, [[SOB]]		**[[Anemia]]: [[weakness]], easy [[fatigue\|fatigability]], [[SOB]]
	**[[Neutropenia]]: infections		**[[Neutropenia]]: infections
	**[[Thrombocytopenia]]: ~~ginvival~~ bleeding/enlargement, ecchymoses, [[epistaxis]], [[Vaginal Bleeding (Non-Pregnant)\|menorrhagia]]		**[[Thrombocytopenia]]: gingival bleeding/[[gingival hyperplasia\|enlargement]], ecchymoses, [[epistaxis]], [[Vaginal Bleeding (Non-Pregnant)\|menorrhagia]]

	==Differential Diagnosis==		==Differential Diagnosis==
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	*[[CXR]]		*[[CXR]]
	*CBC with peripheral smear		*CBC with peripheral smear
	*Chem7, ca, mg, phos, Uric Acid, UA, LDH (to check for ~~Tumor Lysis~~)		*Chem7, ca, mg, phos, Uric Acid, [[UA]], LDH (to check for [[tumor lysis syndrome]])
	*LFTs, Coags, FDP, D-Dimer, Haptoglobin, Fibrinogen (to check for DIC)		*LFTs, Coags, FDP, D-Dimer, Haptoglobin, Fibrinogen (to check for [[DIC]])
	*ESR, CRP		*ESR, CRP
	*Reticulocyte count in anemia		*Reticulocyte count in anemia
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	==Management==		==Management==
	*Aggressive IV hydration		*Aggressive [[IV hydration]]
	*If febrile, complete cultures and broad spectrum antibiotics		*If [[neutropenic fever\|febrile]], complete cultures and broad spectrum [[antibiotics]]
	*Manage Complications		*Manage Complications
	**See [[DIC]]		**See [[DIC]]

Mholtz: Text replacement - "==Treatment==" to "==Management=="

2017-12-11T09:30:41Z

Text replacement - "==Treatment==" to "==Management=="

← Older revision		Revision as of 09:30, 11 December 2017
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	*Get extra purple top for flow cytometry, especially before transfusion		*Get extra purple top for flow cytometry, especially before transfusion

	==~~Treatment~~==		==Management==
	*Aggressive IV hydration		*Aggressive IV hydration
	*If febrile, complete cultures and broad spectrum antibiotics		*If febrile, complete cultures and broad spectrum antibiotics

ClaireLewis: /* Clinical Features */

2017-02-25T23:15:41Z

Clinical Features

← Older revision		Revision as of 23:15, 25 February 2017
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	==Clinical Features==		==Clinical Features==
	*Presents with ~~anemia, neutropenia, thrombocytopenia,~~		*Presents with symptoms of:
	*~~Weakness~~, easy fatigability, infections~~, gingival~~ bleeding/enlargement, ecchymoses, epistaxis, menorrhagia		**[[Anemia]]: [[weakness]], easy fatigability, [[SOB]]
			**[[Neutropenia]]: infections
			**[[Thrombocytopenia]]: ginvival bleeding/enlargement, ecchymoses, [[epistaxis]], [[Vaginal Bleeding (Non-Pregnant)\|menorrhagia]]

	==Differential Diagnosis==		==Differential Diagnosis==

Rossdonaldson1: Text replacement - ">" to ">"

2017-01-23T19:47:19Z

Text replacement - ">" to ">"

← Older revision		Revision as of 19:47, 23 January 2017
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	*Most common acute leukemia in adults (around 80% of cases)		*Most common acute leukemia in adults (around 80% of cases)
	*65 yo median age of diagnosis, Male:Female 5:3		*65 yo median age of diagnosis, Male:Female 5:3
	*Characterized by clonal proliferation of myeloid precursors(blast cells ~~>~~20% in the periphery)		*Characterized by clonal proliferation of myeloid precursors(blast cells >20% in the periphery)

	==Clinical Features==		==Clinical Features==

Kxl328 at 00:33, 20 January 2017

2017-01-20T00:33:51Z

← Older revision		Revision as of 00:33, 20 January 2017
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	*Chem7, ca, mg, phos, Uric Acid, UA, LDH (to check for Tumor Lysis)		*Chem7, ca, mg, phos, Uric Acid, UA, LDH (to check for Tumor Lysis)
	*LFTs, Coags, FDP, D-Dimer, Haptoglobin, Fibrinogen (to check for DIC)		*LFTs, Coags, FDP, D-Dimer, Haptoglobin, Fibrinogen (to check for DIC)
			*ESR, CRP
			*Reticulocyte count in anemia
	*Get extra purple top for flow cytometry, especially before transfusion		*Get extra purple top for flow cytometry, especially before transfusion

Kxl328 at 22:20, 18 January 2017

2017-01-18T22:20:34Z

← Older revision		Revision as of 22:20, 18 January 2017
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	==References==		==References==
			*Janz TG, Hamilton GC: Anemia, Polycythemia and White Blood Cell Disorders, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2014, (Ch) 121:p 1586-1605.
	[[Category:Heme/Onc]]		[[Category:Heme/Onc]]

Kxl328 at 22:20, 18 January 2017

2017-01-18T22:20:05Z

← Older revision		Revision as of 22:20, 18 January 2017
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	==Background==		==Background==
	*~~aka~~ Acute myelogenous leukemia or non-lymphocytic leukemia		*AKA Acute myelogenous leukemia or non-lymphocytic leukemia
	*Most common acute leukemia in adults (around 80% of cases)		*Most common acute leukemia in adults (around 80% of cases)
	*~~65yo~~ median age of diagnosis, Male:Female 5:3		*65 yo median age of diagnosis, Male:Female 5:3
	*~~characterized~~ by clonal proliferation of myeloid precursors(blast cells >20% in the periphery)		*Characterized by clonal proliferation of myeloid precursors(blast cells >20% in the periphery)

	==Clinical Features==		==Clinical Features==
	*Presents with anemia, neutropenia, thrombocytopenia,		*Presents with anemia, neutropenia, thrombocytopenia,
	*~~weakness~~, easy fatigability, infections, gingival bleeding/enlargement, ecchymoses, epistaxis, menorrhagia		*Weakness, easy fatigability, infections, gingival bleeding/enlargement, ecchymoses, epistaxis, menorrhagia

	==Differential Diagnosis==		==Differential Diagnosis==
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	*If febrile, complete cultures and broad spectrum antibiotics		*If febrile, complete cultures and broad spectrum antibiotics
	*Manage Complications		*Manage Complications
	**~~see~~ [[DIC]]		**See [[DIC]]
	**~~see~~ [[Leukostasis]]		**See [[Leukostasis]]
	**~~see~~ [[Hyperviscosity syndrome]]		**See [[Hyperviscosity syndrome]]
	**~~see~~ [[Tumor Lysis Syndrome]]		**See [[Tumor Lysis Syndrome]]
	**~~see~~ [[Retinoic acid syndrome]]		**See [[Retinoic acid syndrome]]

	==See Also==		==See Also==

ClaireLewis: /* Treatment */

2016-12-22T21:46:07Z

Treatment

← Older revision		Revision as of 21:46, 22 December 2016
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	**see [[DIC]]		**see [[DIC]]
	**see [[Leukostasis]]		**see [[Leukostasis]]
			**see [[Hyperviscosity syndrome]]
	**see [[Tumor Lysis Syndrome]]		**see [[Tumor Lysis Syndrome]]
	**see [[Retinoic acid syndrome]]		**see [[Retinoic acid syndrome]]

Rossdonaldson1: Text replacement - "CXR" to "CXR"

2016-09-09T10:00:32Z

Text replacement - "*CXR" to "*CXR"

← Older revision		Revision as of 10:00, 9 September 2016
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	==Evaluation==		==Evaluation==
	*CXR		*[[CXR]]
	*CBC with peripheral smear		*CBC with peripheral smear
	*Chem7, ca, mg, phos, Uric Acid, UA, LDH (to check for Tumor Lysis)		*Chem7, ca, mg, phos, Uric Acid, UA, LDH (to check for Tumor Lysis)

Neil.m.young: Text replacement - " ==" to "=="

2016-08-03T19:34:44Z

Text replacement - " ==" to "=="

← Older revision		Revision as of 19:34, 3 August 2016
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	==Background ==		==Background==
	*aka Acute myelogenous leukemia or non-lymphocytic leukemia		*aka Acute myelogenous leukemia or non-lymphocytic leukemia
	*Most common acute leukemia in adults (around 80% of cases)		*Most common acute leukemia in adults (around 80% of cases)
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	*Get extra purple top for flow cytometry, especially before transfusion		*Get extra purple top for flow cytometry, especially before transfusion

	==Treatment ==		==Treatment==
	*Aggressive IV hydration		*Aggressive IV hydration
	*If febrile, complete cultures and broad spectrum antibiotics		*If febrile, complete cultures and broad spectrum antibiotics
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	**see [[Retinoic acid syndrome]]		**see [[Retinoic acid syndrome]]

	==See Also ==		==See Also==
	*[[Oncologic emergencies]]		*[[Oncologic emergencies]]
	*[[Acute leukemia]]		*[[Acute leukemia]]

Acute myeloid leukemia - Revision history

ClaireLewis at 23:22, 30 September 2019

Mholtz: Text replacement - "==Treatment==" to "==Management=="

ClaireLewis: /* Clinical Features */

Rossdonaldson1: Text replacement - ">" to ">"

Kxl328 at 00:33, 20 January 2017

Kxl328 at 22:20, 18 January 2017

Kxl328 at 22:20, 18 January 2017

ClaireLewis: /* Treatment */

Rossdonaldson1: Text replacement - "*CXR" to "*CXR"

Neil.m.young: Text replacement - " ==" to "=="

Rossdonaldson1: Text replacement - "CXR" to "CXR"